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Human Physiology Laboratory (BIOL 3120 ) PEX-03-01 - Physio Ex 9.1

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University

University of Houston-Downtown

Name: Steffany A. Rivera
Exercise 3: Neurophysiology of Nerve Impulses: Activity 1: The Resting Membrane Potential Lab Report
Pre-lab Quiz Results
You scored 100% by answering 4 out of 4 questions correctly.
1. What is the approximate concentration of K+ inside a typical cell (intracellular concentration)?

2. What is the approximate concentration of K+ outside a cell (extracellular concentration)?

3. What is the approximate concentration of Na+ inside a cell (intracellular concentration)?

4. What is the approximate concentration of Na+ outside a cell (extracellular concentration)?

Experiment Results
Predict Question:
Predict Question: Predict what will happen to the resting membrane potential if the extracellular K+ concentration is
increased.

Stop & Think Questions:
What is the polarity of the resting membrane potential (voltage)?

What does it mean that the voltage just inside the membrane is negative?

The membrane of most cells, including neurons, contains passive, open,
K+ leak channels. Given the normal K+ concentrations and the resultant concentration gradient, which direction would K+
be expected to move (diffuse) through these leak channels?

What effect does increasing extracellular K+ have on the net diffusion of K+ out of the cell?

Which way would Na+ move across the membrane if there were open Na+ channels?

The membrane has open K+ channels, and changing extracellular K+ concentration results in a change in membrane
potential. Changing the extracellular Na+ concentration does not significantly change the membrane potential. What do
your results suggest about the number or state (open or closed) of Na+ channels in the resting membrane of a neuron?

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 Human Physiology Laboratory (BIOL 3120 ) PEX-03-01 - Physio Ex 9.1

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