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NUR2212 What Is Diabetes Insipidus And Siadh

John Marsh
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What is Diabetes Insipidus and Siadh

  • Miami Dade College
  • Advanced Medical-Surgical Nursing (NUR2212)

What is Diabetes Insipidus and SIADH?
This is where the body has a problem producing ADH (either too much or not enough). What is
ADH? It is anti-diuretic hormone. This hormone is produced in the hypothalamus, and stored
and eventually released in the posterior pituitary gland. In order to understand diabetes
insipidus and SIADH, you MUST understand how ADH works because ADH plays an important
role in both DI an SIADH.
Lecture on SIADH and DI
Key Points to Remember about SIADH and DI
 Each condition is related the secretion of ADH (anti-diuretic hormone also called
vasopressin) which plays a major role in how the body RETAINS water and constricts
major blood vessels.
 Each condition presents oppositely of each other (ex: in SIADH the patient retains water
vs. DI where the patient loses water)—-Remember they are opposite of each other!
 Diabetes Insipidus and Diabetes Mellitus are two separate conditions and are not
related although they share the name “Diabetes”.
How does the Anti-diuretic Hormone work?
ADH is produced in the hypothalamus and secreted/stored by the posterior pituitary gland.
The function of ADH is to cause the body to retain water and constrict blood vessels.
How ADH cause the body to retain water? Through the help for the KIDNEYS! ADH causes the
renal tubules to retain water (in a homeostatic way). ***But if you have too much ADH you
will retain too much water and if you have too little ADH you will urinate all of the water our
of your body!
How to Remember which one is Increased vs Decreased?
Syndrome of Inappropriate Antidiuretic Hormone (SIADH): There is a high level of ADH
(antidiuretic hormone) produced
I like to remember this by the acronym SIADH….S Increased ADH (anti-diuretic hormone)
High Level of ADH equals low urinary output
Diabetes Insipidus: Decreased ADH……..There is a low level of ADH (antidiuretic hormone)
Low Level of ADH equals excessive urinary output



NUR2212 What Is Diabetes Insipidus And Siadh

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