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Nursing II (RNRS 120) Theophylline (Theodur)

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John Marsh
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Illinois Central College

Nursing II (RNRS 120)

Theophylline (Theodur)

– Relaxation of bronchial smooth muscle, resulting in
bronchodilation
– Once the first‑line medication for asthma, now used infrequently
because newer medications are safer and more effective
oral
IV (emergency use only)
– Caffeine
– Phenobarbital, phenytoin, and rifampin decrease theophylline
levels.
– Cimetidine, ciprofloxacin, and other fluoroquinolone antibiotics
increase theophylline levels.
– Pregnancy Risk Category C
– Use cautiously in clients who have heart disease, hypertension,
liver and kidney dysfunction, and diabetes mellitus.
– Use cautiously in children and older adults
– Mild toxicity reaction can include GI distress and
restlessness.
– More severe reactions can occur with higher therapeutic
levels and can include dysrhythmias and seizures.
Oral theophylline is used for long-term
control of chronic asthma or COPD.

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Nursing II (RNRS 120) Theophylline (Theodur)

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