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Nursing (Nurs 132) Pharmacology Card List With Classes

John Marsh
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Community College of Philadelphia

Nursing (Nurs 132)

Pharmacology card list with classes (Auto Recovered)

Pharmacology card list with classes
Central nervous system depressants & muscle relaxants
 Sedative – hypnotics 28: Barbiturates (infrequently used bc of their side effects)
a. Benzodiazepines 1 – Schedule IV
 MOA: depress activity in hypothalamus, thalamus, and limbic system.
 Indications: sedation, sleep induction, skeletal muscle relaxation, decrease anxiety.
 Interactions: kava & valerian (herbal versions of drug); risk with other CNS
depressants, grapefruit juice can alter its drug absorption
 See change in sedation before see change of RR
 Muscle relaxants 23
a. Baclofen 24 (centrally acting)
a. Spinal cord injuries, multiple sclerosis, cerebral palsy
b. MOA: enhance inhibitory effects of GABA on the receptors in the spinal cord
Centrally Acting:
 Contraindications: allergies, severe renal impairment; MAOI antidepressants &
 Adverse effects: euphoria, lightheadedness, dizziness, drowsiness, fatigue,
muscle weakness.
 Interactions: caution with other CNS depressants
 Implications: start with low dose, encourage fluid and fiber for constipation,
diabetic patients may require increased oral antidiabetic agent or insulin b/c
baclofen can increase glucose.
b. Dantrolene 23(peripherally acting)
a. Multiple sclerosis, cerebral palsy, prevent and treat hyperthermia, CVA
b. MOA: inhibit calcium release; block muscle contraction
Peripherally Acting:
 side/adverse effects: muscle weakness, drowsiness, dizziness, liver toxicity at
high dose
 Contraindications: patient with liver disease
 Interactions: IV dantrolene use in addition to CCB can increase risk for
 Implications: monitor diarrhea, liver function and avoid alcohol. Report muscle
weakness & prolonged diarrhea

 CNS Stimulants:
a. broad class of medications that stimulate areas of the brain and spinal cord
b. stimulate excitatory neurotransmitters int eh brain: dopamine,
norepinephrine, and serotonin
b. ADHD//Narcolepsy Agent 11
a. MOA: stimulate areas of cerebral cortex and thalamus of the brain associated
with mental alertness.
b. Indication: treat ADHA and narcolepsy
c.Contraindications: increased HR, allergy, anxiety/agitation, glaucoma
d. Adverse effects: *nervousness*, “speed up” body systems, inc HR & BP,
insomnia, tremor
e. Interactions: digoxin (HR abnormality), risk with other CNS stimulant drug
c. Anorexiants (ex: diet pills) no card
 MOA: suppresses appetite control center of brain
 Indications: treatment of obesity
 Contraindications: allergy, severe cardiovascular disease, uncontrolled hypertension,
hyperthyroidism, glaucoma, hx drug abuse, eating disorder
 Adverse effects: inc. HR (tachycardia)
 Interactions: risk with other CNS stimulant drug, usually taken not past 3pm
d. Antimigraine Drug Ex: zolmitriptan (zomig) Triptan -104
a. MOA: Triptans (serotonin receptor agonists) act by stimulating receptors in
cebral arteries to vasoconstrict, and reduce neurogenic inflammation
b. Indications: used for acute migraine headache
c.Contraindications: allergy, serious cardiovascular disease due to vasoconstriction
d. Adverse effects: vasoconstrictive effects (hypertension, tachycardia,
palpations) or congested feeling of heart or chest
e. Interactions: co-administration with Ergot alkaloids
f. *Abortive therapy: cannot take a triptan to prevent a migraine—only AFTER migraine
has started
e. Analeptics (no card) (drugs for respiratory depression) –typically given in ICU
 MOA: stimulates the medulla and the spinal cord that control respiration.
Relaxes smooth muscle in respiratory tract, dilates pulmonary arterioles,
stimulates general CNS.
 Indications: used for neonatal apnea, bronchopulmonary, dysplasia…
 Contraindications: allergy, peptic ulcer disease and serious cardiovascular
 Adverse Effects: increase gastric secretion (vagal), diarrhea, reflex tachycardia,
flushing, sweating
 Interactions: risk with other CNS stimulants



Nursing (Nurs 132) Pharmacology Card List With Classes

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