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Nursing Therapeutics And Pharmacologic Management In Patient (NRS 115) Cefazolin Unit 2

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John Marsh
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College of Staten Island CUNY

Nursing Therapeutics And Pharmacologic Management In Patient (NRS 115)

Cefazolin Unit 2

Student Name: Samantha Mendoza
Classification: Antibiotics, First-generation cephalosporins
Generic Name: Cefazolin
Expected Pharmacological Action: Cefazolin inhibits the third and last
step of bacterial wall synthesis by binding to one or more penicillin-binding
proteins.
Usual Dose: IM, IV 1–1.5 g every 8 h (max dose 12 g/d)
Usual routes: IM, IV
Therapeutic Uses: Expected Common
Adverse Effects:
 Active against streptococci,
staphylococci, Neisseria,
Salmonella, Shigella, Escherichia,
Klebsiella, Listeria, Bacillus,
Haemophilus influenzae,
Corynebacterium diphtheriae,
Proteus mirabilis, and Bacteroides
(except B. fragilis)
 Clinical indications for the use
of the cephalosporins include
surgical prophylaxis and
treatment of infections of the
respiratory tract, skin and soft
tissues, bones and joints, urinary
tract, brain and spinal cord, and
bloodstream (septicemia).

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Nursing Therapeutics And Pharmacologic Management In Patient (NRS 115) Cefazolin Unit 2

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