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Pathophysiology And Pharmacology For Nursing Practice I (NUR 371) Patho Assignment 1

James Moore
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Pathophysiology And Pharmacology For Nursing Practice I (NUR 371)

Assignment 1 – Ankle swelling and fatigue in a 60yo.

1) Considering the Starling forces (not cardiac Frank-Starling law) affecting fluid movement in a capillary, describe two ways to promote an increase in net fluid movement into the interstitium (i.e. increase/decrease in a given force that is part of calculating net fluid movement). (2pts) (MO 2,3; i.e. Relates to Module Objectives 2 & 3 as found under Module 1 Overview)

2) Given the Starling forces that can promote movement describe above, list three organs that need to be evaluated because of their ability to promote such edema and why (i.e. how is the Starling forces altered by dysregulation of that organ). (6pts) (MO 1,2,3

3) Describe why he is having shortness of breath using Starling forces terminology. (2pts) (MO 2,3)

4) Describe how interstitial fluid compares to plasma. Is interstitial fluid intracellular or extracellular? (2pts) (MO 1,2)

5) Given the above information, you diagnose him with congestive heart failure. You consider various medications for his treatment, which aim to improve his cardiac function by slowing the rate and increasing contractility. Digoxin is one such drug (though it does appear to have a20% higher all-cause mortality rate in atrial fibrillation patients, so it is not given without careful consideration). How does digoxin work in terms of altering movement of Na+, K+ and Ca++ and how does that relate to the improvement in cardiac function (increased contractility and slower heart rate)? (5pts) (MO 1,2)

6) In general, what is the most common cause of sore throat in children 15yo and younger? (2pts)(MO 9

7) Why is it important to treat strep throat within the first nine days or so? What is the mechanism for damage beyond the throat area (rare, serious complications) if left untreated? (6pts) (MO 9)

8) During alkalosis, as can occur from vomiting and or diarrhea, causes what kind of shift in K+ concentrations occur (regarding fluid compartments, i.e. extracellular (plasma and interstitial) vs intracellular) and thus may show up in blood chemistry readings? (1pt) (MO 1,3,4).



Pathophysiology And Pharmacology For Nursing Practice I (NUR 371) Patho Assignment 1

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