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Pharmacological Basis (NUR 3192) Otic Drugs Notes

John Marsh
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Nova Southeastern University

Pharmacological Basis For Nursing Interventions II (NUR 3192)

Otic pharm – otic drugs notes

Pharm II Otic Drugs Final
Ear Disorders
• Bacterial and fungal infections
• Inflammatory disorders that cause pain
• Earwax accumulation
• External ear: physical trauma, dermatitis
• Middle ear: otitis media (middle ear infection) has to be treated with systemic drugs (amoxicillin first line)
o Most often afflicts children, following a respiratory tract infection do not start ABX until fever is
o In adults usually results from foreign objects or water sports
o Symptoms include pain, fever, malaise, pressure, sensation of fullness in the ears, hearing loss
o If untreated, tinnitus, nausea, vertigo, mastoiditis may occur
o Hearing deficits and hearing loss may result if prompt
therapy not started
Antibacterial and Antifungal Otic Drugs
• Topical formulations applied to the external ear for otitis
• Often combined with steroids for antiinflammatory,
antipruritic, and antiallergic drug effects
• Middle ear infections generally require systemically
administered antibiotics PO, IV, IM
• Antibiotics combination products contain ABX & steroid
o neomycin and polymyxin B plus hydrocortisone
combination (Cortisporin Otic)
o Others containing ciprofloxacin



Pharmacological Basis (NUR 3192) Otic Drugs Notes

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