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Primary Concepts Of Adult Nursing (NUR 3180) Leukemia

John Marsh
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Nova Southeastern University

Primary Concepts Of Adult Nursing (NUR 3180)


Leukemia Ch. 34
 Hematopoietic malignancy characterized by unregulated proliferations of leukocytes
 Classified by stem cell
 Lymphoid
 Myeloid
 Classified as acute or chronic
Acute Myeloid Leukemia
 Defect in hematopoietic stem cell that differentiates into all myeloid cells
 Any age group affected: infrequently occurs before age 55
 Most common non-lymphocytic leukemia
 Prognosis is variable
 Increased risk in those patient who have received alkylating agents for cancer (worse prognosis)
Chronic Myeloid Leukemia
 Mutation in the myeloid stem cell
 Pathologic increase in production of blast cells
 BCR-ABL gene present in almost all patients with CML
 Uncommon in patients < 20 years of age
 10-15% of all leukemia’s
Acute Lymphocytic Leukemia
• Uncontrolled proliferation of immature cells (lymphoblasts) derived from the lymphoid stem cell
• B-lymphocyte or T-lymphocyte precursor
• ALL is most common in young children (boys> girls)
• Peaks at age 4
• Responsive to treatment
• Complete remission achievable
Chronic Lymphocytic Leukemia
• Common



Primary Concepts Of Adult Nursing (NUR 3180) Leukemia

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